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San Diego (, Spanish: [san ˈdjeɣo]; Spanish for 'Saint Didacus') is a city in the U.S. state of California on the coast of the Pacific Ocean, approximately 110 miles (180 km) southeast of downtown Los Angeles and immediately adjacent to the border with Mexico. With an estimated population of 1,423,851 as of July 1, 2019, San Diego is the eighth-largest city in the United States and second-largest in California. It is part of the San Diego–Tijuana conurbation, the second-largest transborder agglomeration between the U.S. and a bordering country after Detroit–Windsor, with a population of 4,922,723 people. The city is known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the United States Navy, and recent emergence as a healthcare and biotechnology development center.
San Diego has been called "the birthplace of California". Historically home to the Kumeyaay people, it was the first site visited by Europeans on what is now the West Coast of the United States. Upon landing in San Diego Bay in 1542, Juan Rodríguez Cabrillo claimed the area for Spain, forming the basis for the settlement of Alta California 200 years later.
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Caral-Supe (also known as Caral and Norte Chico) was a complex pre-Columbian-era society that included as many as thirty major population centers in what is now the Caral region of north-central coastal Peru. The civilization flourished between the fourth and second millennia BC, with the formation of the first city generally dated to around 3500 BC, at Huaricanga, in the Fortaleza area. It is from 3100 BC onward that large-scale human settlement and communal construction become clearly apparent, which lasted until a period of decline around 1800 BC. Since the early twenty-first century, it has been established as the oldest-known civilization in the Americas.
This civilization flourished along three rivers, the Fortaleza, the Pativilca, and the Supe. These river valleys each have large clusters of sites. Farther south, there are several associated sites along the Huaura River. The alternative name, Caral-Supe, is derived from the city of Caral in the Supe Valley, a large and well-studied Caral-Supe site.
Complex society in Caral-Supe arose a millennium after Sumer in Mesopotamia, was contemporaneous with the Egyptian pyramids, and predated the Mesoamerican Olmec by nearly two millennia.
In archaeological nomenclature, Caral-Supe is a pre-ceramic culture of the pre-Columbian Late Archaic; it completely lacked ceramics and apparently had almost no visual art.