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Macau ( (listen); 澳門, Cantonese: [ōu.mǔːn]; Portuguese: [mɐˈkaw]), also spelled Macao and officially the Macao Special Administrative Region of the People's Republic of China, is a city and special administrative region of the People's Republic of China in the western Pearl River Delta by the South China Sea. With a population of about 650,000 and an area of 32.9 km2 (12.7 sq mi), it is the most densely populated region in the world.
Macau is a former colony of the Portuguese Empire, after Ming China leased the territory as a trading post in 1557. Portugal paid an annual rent and administered the territory under Chinese sovereignty until 1887, when it gained perpetual colonial rights in the Sino-Portuguese Treaty of Peking. The colony remained under Portuguese rule until 1999, when it was transferred to China. Macau is a special administrative region of China, which maintains separate governing and economic systems from those of mainland China under the principle of "one country, two systems".
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Medellín (Spanish pronunciation: [meðeˈʝin] or [meðeˈʎin]), officially the Municipality of Medellín (Spanish: Municipio de Medellín), is the second-largest city in Colombia, after Bogotá, and the capital of the department of Antioquia. It is located in the Aburrá Valley, a central region of the Andes Mountains in South America. According to the National Administrative Department of Statistics, the city had an estimated population of 2,508,452 according to the 2018 census. With its surrounding area that includes nine other cities, the metropolitan area of Medellín is the second-largest urban agglomeration in Colombia in terms of population and economy, with more than 3.7 million people.
In 1616 the Spaniard Francisco Herrera Campuzano erected a small indigenous village ("poblado") known as "Saint Lawrence of Aburrá" (San Lorenzo de Aburrá), located in the present-day El Poblado commune. On 2 November 1675, the queen consort Mariana of Austria founded the "Town of Our Lady of Candelaria of Medellín" (Villa de Nuestra Señora de la Candelaria de Medellín) in the Aná region, which today corresponds to the center of the city (east-central zone) and first describes the region as "Medellín". In 1826, the city was named the capital of the Department of Antioquia by the National Congress of the nascent Republic of Gran Colombia, comprised by present-day Colombia, Venezuela, Ecuador, and Panama. After Colombia won its independence from Spain, Medellín became the capital of the Federal State of Antioquia until 1888, with the proclamation of the Colombian Constitution of 1886. During the 19th century, Medellín was a dynamic commercial center, first exporting gold, then producing and exporting coffee.
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