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San Diego (, Spanish: [san ˈdjeɣo]; Spanish for 'Saint Didacus') is a city in the U.S. state of California on the coast of the Pacific Ocean, approximately 110 miles (180 km) southeast of downtown Los Angeles and immediately adjacent to the border with Mexico. With an estimated population of 1,423,851 as of July 1, 2019, San Diego is the eighth-largest city in the United States and second-largest in California. It is part of the San Diego–Tijuana conurbation, the second-largest transborder agglomeration between the U.S. and a bordering country after Detroit–Windsor, with a population of 4,922,723 people. The city is known for its mild year-round climate, natural deep-water harbor, extensive beaches, long association with the United States Navy, and recent emergence as a healthcare and biotechnology development center.
San Diego has been called "the birthplace of California". Historically home to the Kumeyaay people, it was the first site visited by Europeans on what is now the West Coast of the United States. Upon landing in San Diego Bay in 1542, Juan Rodríguez Cabrillo claimed the area for Spain, forming the basis for the settlement of Alta California 200 years later.
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